The ART of
becoming parents

Steps of the egg donation treatment

We have a huge experience of distant egg donation at Scanfert. We’ve built up this process so that it has maximum effectiveness, simplicity and low stress for our patients. 90% of treatment can be carried out in your home country and you have to come to the Scanfert clinic for egg and sperm collection and embryo transfer only once.

There are 3 people involved in egg donation treatment: the egg donor, the egg recipient and sperm provider (your partner or sperm donor). All our egg donors are women under 32 who have own children and who have had a thorough medical checkup. We collect their photos as children and as adults, as well as their family medical history. If you would like to use eggs of your own donor (a friend or relative), we can organize this as well.

Step 1. Making egg donor choice with the help of our egg donation team

We have our own extensive database of donors. After you fill out the questionnaire our specialists will choose several variants that are most suitable for you and provide you access to their profiles and photos both when a child and an adult.

Step 2. Synchronizing the menstrual cycles

If you are going to have an IVF with your own eggs, no synchronizing is needed. But when IVF with donor eggs is going to be made, the menstrual cycles of the recipient and the donor should be synchronized. Treatment starts at the beginning of donor’s cycles by taking hormones . Even if a woman has irregular cycle or doesn’t have it at all, the pills help it to start at the right time. Sometimes several cycles are needed for the uterine lining to grow before the embryo transfer is made. The pills are finished by the donor and the recipient on the same day, causing menstruation for both.  Now the women are ready for further treatment.

Step 3. The egg donor treatment

When the egg donor’s menstruation starts, she undergoes ultrasound scan to be certain that her ovaries are inactive and the uterine lining is thin. After, the donor gets stimulation for her ovaries to produce eggs. In a few days she gets another medication to prevent premature eggs release. Later more ultrasound examinations are made to control the medication effect and to monitor the follicles growth. In around 10 days after the stimulation starts the donor takes another pills to make her eggs ready for retrieval. The retrieval is carried out under general anesthetic. A needle is introduced into the ovary via the vagina and aspirates the eggs from the follicles. All the retrieved eggs will be available for your treatment.

Step 4. The egg recipient treatment

At Scanfert you’ll get your personal treatment plan. Our first concern is to solve the problems which may reduce chances for successful embryo transfer and further treatment. After, you will get hormonal medication. When you stop it, the menstruation (the so-called withdrawal bleed) starts, whether you’ve had it previously or not. It may take several cycles to be sure that the uterine lining responds the treating well.

During your treatment you will get medication suppressing premature ovulation and ensuring that implantation window is optimal and synchronized with the donor. We’re aimed at bringing your womb to the best condition to receive the precious embryos successfully. This means you’ll need to take estrogen pills, patches or cream. Several days before embryo transfer you’ll need to take progesterone as well. And of course, you will have ultrasound checks to see if the lining of your uterus is ready for the transfer.

Step 5. The partner

The sperm of your partner for the IVF could be used in two forms:

  1. Your partner can deliver it on the day of your first visit to Scanfert. The sperm will be frozen and thawed on the day of the eggs retrieval. This will make embryo transfer visit quicker.
  2. We can use fresh sperm, which your partner delivers on the day of egg retrieval.

We advise your partner not to have an ejaculation for 2-5 days before collecting his sperm for freezing or for fertilization (neither during sexual intercourse, nor through masturbation). Collection of sperm can be done both in our clinic (in a private room) or at your hotel. Just be sure to bring it not later than an hour after ejaculation and to keep it at room temperature.

Step 6. Fertilization and embryo transfer

After the eggs and the sperm are collected, the eggs are fertilized with the sperm. They stay at our laboratory for five days, where they grow and develop into embryos, called blastocytes. Our embryologists determine the most viable and the most hopeful embryos. On a set day the fast and painless embryo transfer is made: one or two embryos are transferred into the uterus through the cervical canal using a thin soft catheter.

You can decide how much embryos will be transferred, according to our recommendations. Usually we transfer one high-quality fresh embryos, and if it doesn’t work, we transfer two frozen embryos the next cycle.

We basically recommend to transfer one high quality embryo, because transferring two of them doesn’t increase the chances of success significantly, but increases the chances of twin pregnancy, which is 5-6 times more complicated both for mother and children.

In 2017 donor egg pregnancy rate at Scanfert was 72% in fresh cycle and 57% in frozen cycle.

Step 7. Treatment after embryo transfer

Two weeks after embryo transfer you can make a pregnancy test with your blood or urine. If it is positive you should confirm it via ultrasound monitoring two more weeks later. All this time you should continue to take estrogen and progesterone till the 12th week of pregnancy and then you should only take progesterone till the 30th pregnancy week.

We kindly ask all our patients to keep us informed on their news. If they are pregnant, we would be happy to know about your progress and to keep in touch with you if you have any complications.

If your pregnancy doesn’t happen this time, the medication can be cancelled. In this case we’ll do our best to help you reach your dream finally.

Step 8. Cryopreservation of remaining embryos

If there are excessive embryos which are not going to be transferred in the current cycle, they can be frozen via cryopreservation on the 5th or 6th day. They are your property and can be used in further attempts to get pregnant, or if you want another child in the future.

The main benefit of embryo freezing is that you don’t need to be stimulated once again, no sperm needs to be collected. The procedure becomes cheaper and quicker, though the preparation of the uterus is still needed.

About cryopreservation

Embryo cryopreservation is preservation by subjection to extremely low temperatures. The first baby from a frozen embryo in the world was born in 1984. By 2008, up to 500 000 babies from frozen embryos were delivered. It is even known about the pregnancies with the embryos frozen for 16 years. Numerous examinations showed no risks of birth abnormalities increase for children born from the frozen embryos.

The research in this field continues, and human embryos methods continue to be improved. Today the most up to date and effective way of embryos cryopreservation is vitrification, a super fast freezing method, which has more advantages than slow-freezing.

Scanfert and AVA-Peter embryo cryobank is one of the largest in Russia.  Vitrification is being performed since 2008 with the help of Kuwayama method and Cryotop systems. The results of this work are consistent with the conclusions of European researches, showing higher pregnancy rate when using vitrification:

Comparative results of vitrification and slow freezing are:

  Vitrification, day 5 Vitrification, day 6 Slow freezing

Average survival rate of embryos

77%

78,5%

62%

Implantation rate

30%

Clinical pregnancy rate

43%

47%

26%

Pregnancy loss rate

21%

13%

26%

 

Unsure about your own chances? Interested in a program with guarantee?
Please, write us!